Li Zhang, PhD

Associate Professor
Medicine
+1 415 476-5339

Li Zhang, PhD is an Associate Professor in the UCSF Department of Medicine and Department of Epidemiology and Biostatistics. She is an associate member of the UCSF Helen Diller Family Comprehensive Cancer Center (HDFCCC). Professor Zhang has over 15 years of experience in applying statistical methods in medical research, including epidemiology studies, basic science studies, clinical trials design, and high-throughput sequencing data. Her statistical methodological interests are cancer epidemiology and immunoinformatics. Currently, Professor Zhang serves on the Global Action Plan 6 Project Steering Committee for the Movember Foundation and the American Society of Clinical Oncology Career Development Award as a statistical reviewer. She has more than 60 publications. 

Publications: 

High-Dose Abiraterone Acetate in Men With Castration Resistant Prostate Cancer.

Clinical genitourinary cancer

Friedlander TW, Graff JN, Zejnullahu K, Anantharaman A, Zhang L, Paz R, Premasekharan G, Russell C, Huang Y, Kim W, Aggarwal RR, Lin AM, Fong L, Alumkal JJ, Beer TM, Sharifi N, Alyamani M, Dittamore R, Small EJ, Paris PL, Ryan CJ

Choice of ANesthesia for EndoVAScular Treatment of Acute Ischemic Stroke: Protocol for a randomized controlled (CANVAS) trial.

International journal of stroke : official journal of the International Stroke Society

Peng Y, Li Y, Jian M, Liu X, Sun J, Jia B, Dong J, Zeng M, Lin N, Zhang L, Gelb AW, Chan MT, Han R

A multicenter phase I study of cabazitaxel, mitoxantrone, and prednisone for chemotherapy-naïve patients with metastatic castration-resistant prostate cancer: A department of defense prostate cancer clinical trials consortium study.

Urologic oncology

Aggarwal R, Bryce A, Ryan CJ, Harzstark A, Derleth C, Kim W, Friedlander T, Lin AM, Rodvelt-Bagchi T, Dhawan M, Zhang L, Lee M, Siebeneck E, Hough J, Small EJ

Systemic GM-CSF Recruits Effector T Cells into the Tumor Microenvironment in Localized Prostate Cancer.

Cancer immunology research

Wei XX, Chan S, Kwek S, Lewis J, Dao V, Zhang L, Cooperberg MR, Ryan CJ, Lin AM, Friedlander TW, Rini B, Kane C, Simko JP, Carroll PR, Small EJ, Fong L

Clonotypic Diversification of Intratumoral T Cells Following Sipuleucel-T Treatment in Prostate Cancer Subjects.

Cancer research

Sheikh N, Cham J, Zhang L, DeVries T, Letarte S, Pufnock J, Hamm D, Trager J, Fong L

GM-CSF and ipilimumab therapy in metastatic melanoma: Clinical outcomes and immunologic responses.

Oncoimmunology

Kwek SS, Kahn J, Greaney SK, Lewis J, Cha E, Zhang L, Weber RW, Leonard L, Markovic SN, Fong L, Spitler LE

Preexisting Levels of CD4 T Cells Expressing PD-1 Are Related to Overall Survival in Prostate Cancer Patients Treated with Ipilimumab.

Cancer immunology research

Kwek SS, Lewis J, Zhang L, Weinberg V, Greaney SK, Harzstark AL, Lin AM, Ryan CJ, Small EJ, Fong L

The interface of inflammation and subclinical atherosclerosis in granulomatosis with polyangiitis (Wegener's): a preliminary study.

Translational research : the journal of laboratory and clinical medicine

Hajj-Ali RA, Major J, Langford C, Hoffman GS, Clark T, Zhang L, Sun Z, Silverstein RL

Dose-volume analysis and the temporal nature of toxicity with stereotactic body radiation therapy for prostate cancer.

Practical radiation oncology

Seymour ZA, Chang AJ, Zhang L, Kirby N, Descovich M, Roach M, Hsu IC, Gottschalk AR

The incidence of oesophageal cancer in Eastern Africa: identification of a new geographic hot spot?

Cancer epidemiology

Cheng ML, Zhang L, Borok M, Chokunonga E, Dzamamala C, Korir A, Wabinga HR, Hiatt RA, Parkin DM, Van Loon K

Somatic wiskott-aldrich syndrome protein family member 3 (WASF3) mutations in myelodysplastic syndromes and related myeloid malignancies

Leukemia Research

V. Visconte, A. Tabarroki, L. Zhang, A.T. Gerds, H.J. Rogers, Y. Han, J. Barnard, V. Shivarov, J. Carew, R.V. Tiu

Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts.

Journal of hematology & oncology

Visconte V, Tabarroki A, Zhang L, Parker Y, Hasrouni E, Mahfouz R, Isono K, Koseki H, Sekeres MA, Saunthararajah Y, Barnard J, Lindner D, Rogers HJ, Tiu RV

Bone metastases and skeletal-related events from neuroendocrine tumors.

Endocrine connections

Van Loon K, Zhang L, Keiser J, Carrasco C, Glass K, Ramirez MT, Bobiak S, Nakakura EK, Venook AP, Shah MH, Bergsland EK

Sequential use of the androgen synthesis inhibitors ketoconazole and abiraterone acetate in castration-resistant prostate cancer and the predictive value of circulating androgens.

Clinical cancer research : an official journal of the American Association for Cancer Research

Kim W, Zhang L, Wilton JH, Fetterly G, Mohler JL, Weinberg V, Morse A, Szmulewitz RZ, Friedlander TW, Fong L, Lin AM, Harzstark AL, Molina A, Small EJ, Ryan CJ

Clinicopathologic and molecular characterization of myeloid neoplasms harboring isochromosome 17(q10).

American journal of hematology

Visconte V, Tabarroki A, Zhang L, Hasrouni E, Gerace C, Frum R, Ai J, Advani AS, Duong HK, Kalaycio M, Saunthararajah Y, Sekeres MA, His ED, Shetty S, Rogers HJ, Tiu RV

Multi-parameter assessment of platelet inhibition and its stability during aspirin and clopidogrel therapy.

Thrombosis research

Timur AA, Murugesan G, Zhang L, Barnard J, Bhatt DL, Kottke-Marchant K

Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

American journal of human genetics

Tragante V, Barnes MR, Ganesh SK, Lanktree MB, Guo W, Franceschini N, Smith EN, Johnson T, Holmes MV, Padmanabhan S, Karczewski KJ, Almoguera B, Barnard J, Baumert J, Chang YP, Elbers CC, Farrall M, Fischer ME, Gaunt TR, Gho JM, Gieger C, Goel A, Gong Y, Isaacs A, Kleber ME, Mateo Leach I, McDonough CW, Meijs MF, Melander O, Nelson CP, Nolte IM, Pankratz N, Price TS, Shaffer J, Shah S, Tomaszewski M, van der Most PJ, Van Iperen EP, Vonk JM, Witkowska K, Wong CO, Zhang L, Beitelshees AL, Berenson GS, Bhatt DL, Brown M, Burt A, Cooper-DeHoff RM, Connell JM, Cruickshanks KJ, Curtis SP, Davey-Smith G, Delles C, Gansevoort RT, Guo X, Haiqing S, Hastie CE, Hofker MH, Hovingh GK, Kim DS, Kirkland SA, Klein BE, Klein R, Li YR, Maiwald S, Newton-Cheh C, O'Brien ET, Onland-Moret NC, Palmas W, Parsa A, Penninx BW, Pettinger M, Vasan RS, Ranchalis JE, M Ridker P, Rose LM, Sever P, Shimbo D, Steele L, Stolk RP, Thorand B, Trip MD, van Duijn CM, Verschuren WM, Wijmenga C, Wyatt S, Young JH, Zwinderman AH, Bezzina CR, Boerwinkle E, Casas JP, Caulfield MJ, Chakravarti A, Chasman DI, Davidson KW, Doevendans PA, Dominiczak AF, FitzGerald GA, Gums JG, Fornage M, Hakonarson H, Halder I, Hillege HL, Illig T, Jarvik GP, Johnson JA, Kastelein JJ, Koenig W, Kumari M, März W, Murray SS, O'Connell JR, Oldehinkel AJ, Pankow JS, Rader DJ, Redline S, Reilly MP, Schadt EE, Kottke-Marchant K, Snieder H, Snyder M, Stanton AV, Tobin MD, Uitterlinden AG, van der Harst P, van der Schouw YT, Samani NJ, Watkins H, Johnson AD, Reiner AP, Zhu X, de Bakker PI, Levy D, Asselbergs FW, Munroe PB, Keating BJ

Large Granular Lymphocytic: Common Therapies and their Outcomes

Journal of Hematology and Transfusion

Manuel G. Afable II, Michael J. Clemente, Andres Jerez, Li Zhang, Holleh Husseinzadeh, Hanna Rajala, Satu Mustjoki, Hideki Makishima, Brittney E. Dienes, John Desamito, Alan Lichtin, Mikkael A. Sekeres, Brad Pohlman, Anjali Advani, Ramon V. Tiu, Jaroslaw P. Maciejewski.

Management and outcomes for patients with TTP: analysis of 100 cases at a single institution.

American journal of hematology

Chaturvedi S, Carcioppolo D, Zhang L, McCrae KR

cgaTOH: extended approach for identifying tracts of homozygosity.

PloS one

Zhang L, Orloff MS, Reber S, Li S, Zhao Y, Eng C

Modeling haplotype-haplotype interactions in case-control genetic association studies.

Frontiers in genetics

Zhang L, Liu R, Wang Z, Culver DA, Wu R

Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms.

Blood

Ghosh A, Murugesan G, Chen K, Zhang L, Wang Q, Febbraio M, Anselmo RM, Marchant K, Barnard J, Silverstein RL

Semiparametric Bayesian modeling of random genetic effects in family-based association studies.

Statistics in medicine

Zhang L, Mukherjee B, Hu B, Moreno V, Cooney KA

A Computational Approach to the Functional Clustering of Periodic Gene Expression Profiles

Genetics

Bong-Rae Kim, Li Zhang, Arthur Berg, Jianqing Fan and Rongling Wu

Modeling Unobserved Sources of Heterogeneity in Animal Abundance using a Dirichlet Process Prior

Biometrics

Robert Dorazio, Bhramar Mukherjee, Li Zhang, Malay Ghosh, Howard L. Jelks, and Frank Jordan.

Breast-cancer stromal cells with TP53 mutations and nodal metastases.

The New England journal of medicine

Patocs A, Zhang L, Xu Y, Weber F, Caldes T, Mutter GL, Platzer P, Eng C

Semiparametric Bayesian Analysis of Case-Control Data under Conditional Gene-Environment Independence

Biometrics

Bhramar Mukherjee, Li Zhang, Malay Ghosh and Samiran Sinha

A Bayesian Framework for Genetic Association in Case-Control Studies: Accounting for Unknown Population Substructure

Statistical Modeling

Li Zhang, Bhramar Mukherjee, Malay Ghosh and Rongling Wu.

Equivalence of Posteriors in the Bayesian Analysis of The Multinomial-Poisson Transformation

Metron - International Journal of Statistics

Malay Ghosh, Li Zhang and Bhramar Mukherjee.

A model for estimating joint maternal-offspring effects on seed development in autogamous plants.

Physiological genomics

Zhang L, Yang MC, Wang X, Larkins BA, Gallo-Meagher M, Wu R